For millennia, medicinal mushrooms have held a prominent place in traditional pharmacopoeias (directories of medicinal substances or products and their various uses). Today, modern science is rediscovering and continues to explore their therapeutic properties, particularly those related to their polysaccharides (molecules composed of long chains of simple sugars that promote immunomodulation, cellular protection, and energy support). These complex molecules, the most well-known of which are beta-glucans, are increasingly attracting interest due to their ability to modulate our immune system and promote cellular health.
In this regard, we take you on a journey to discover the fascinating mechanisms by which the polysaccharides of medicinal mushrooms interact with our body. From their molecular structure to their effects on innate and adaptive immunity, as well as digestive and metabolic health, we reveal the specifics of these bioactive compounds.
Polysaccharides: What to Remember?
Polysaccharides are complex molecules formed from chains of sugars linked together. Abundantly present in medicinal mushrooms, these compounds act as cellular modulators, meaning they directly influence the functioning of our cells. Beta-glucans, for example, a specific family of polysaccharides, activate immune receptors on the surface of cells to trigger a defense response against external aggressions.
Their unique structure also allows them to neutralize free radicals, unstable molecules responsible for oxidative stress that damages our cells. At the same time, they promote intercellular communication, essential for coordinating biological processes such as tissue repair or inflammatory regulation. These mechanisms make polysaccharides key allies in preserving the integrity and vitality of our cells.
In which mushrooms are polysaccharides found?
Polysaccharides, particularly beta-glucans, are present in a wide variety of medicinal mushrooms. Among the most studied is the shiitake (Lentinula edodes), famous for its lentinan, a beta-glucan with remarkable immunomodulatory properties.
The reishi (Ganoderma lucidum), the chaga (Inonotus obliquus), and the Lion's Mane mushroom (Hericium erinaceus) are also distinguished by their polysaccharides, which positively influence the gut microbiota.
These medicinal mushrooms, known for their adaptogenic properties and richness in bioactive compounds, are available at French Mush. Our products, grown in Europe according to organic farming standards, offer a natural and effective solution to support your daily well-being.
Moreover, it is fascinating to note that more than 2000 species of edible or medicinal mushrooms contain bioactive polysaccharides. Each of these species has a unique profile that contributes to its specific health effects.
How do polysaccharides affect immunity and cellular health?
The polysaccharides of medicinal mushrooms, particularly beta-glucans, have many beneficial properties for our body. They notably influence immunity and cellular health. But how?
The stimulation of the immune system
Polysaccharides act as powerful immunomodulators by subtly and effectively enhancing our natural defenses. They stimulate the activity of macrophages (cells that eliminate pathogens), as well as that of Natural Killer (NK) cells, which are essential in the fight against infections and cancer cells.
On the other hand, the interaction of beta-glucans with specific receptors, such as Dectin-1, on immune cells triggers defense reactions. This process leads to an increase in the production of cytokines, messenger molecules of the immune system. The result is an enhanced ability to fight bacteria, viruses, and parasites. This overall stimulation of immunity contributes to better resistance of the body against external aggressions.
The effects of polysaccharides on cellular health
Beyond their impact on immunity, the polysaccharides of medicinal mushrooms play a crucial role in maintaining cellular health. Their antioxidant properties protect our cells against damage caused by free radicals. It is important to know that free radicals are unstable molecules that can alter DNA and accelerate cellular aging.
Certain polysaccharides, particularly those from the Reishi mushroom (Ganoderma lucidum), have shown an ability to modulate the gut microbiota. They promote the growth of beneficial bacteria for the body and stimulate the production of short-chain fatty acids. These are essential for the health of our intestines. This action on the microbiota is accompanied by anti-inflammatory effects that reduce the production of pro-inflammatory mediators and strengthen the intestinal barrier.
French Mush: enjoy the benefits of polysaccharides with our adaptogenic mushrooms
At French Mush, we offer a range of adaptogenic mushrooms rich in polysaccharides, particularly beta-glucans, known for their numerous health benefits. Our products, including Reishi, Cordyceps, Chaga, Shiitake, and Lion's Mane, are carefully selected and cultivated according to the strictest organic standards.
Reishi, nicknamed the "mushroom of immortality," is particularly valued for its ability to boost the immune system and improve the lipid profile.
It should be noted that the lipid profile is a set of measurements that assess the different types of fats (lipids) in the blood. This includes:
- total cholesterol
- LDL ("bad" cholesterol)
- HDL ("good" cholesterol)
- triglycerides
The objective is to determine the cardiovascular risk.
Chaga, on the other hand, is known for its powerful antioxidant properties and its potential to regulate blood sugar levels. Lion's Mane, or crinière de lion, is renowned for its beneficial effects on cognitive health and the microbiome.
Our mushroom extracts are obtained through ultrasonic extraction that preserves the integrity of bioactive compounds. By incorporating our adaptogenic mushrooms into your daily routine, you benefit from natural support for your immune system, metabolic balance, and overall well-being.
Sources:
- Medicinal value of edible mushroom polysaccharides: a review
https://www.sciencedirect.com/science/article/pii/S2772566922000696 - Mushroom Polysaccharides: a Potent Immune-Modulator
https://biointerfaceresearch.com/wp-content/uploads/2020/08/20695837112.89158930.pdf
